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Travels to the Nanoworld. Miniature Machinery in Nature and Technology
Hardback: Perseus Books, Cambridge, MA, May 1999,
ISBN 0-306-46008-4, $ 25.95 , 254 + xiii pp.
Paperback: Perseus Books January 2001, ISBN 0-738-20444-7, $ 16.00, 254 + xiii pp.


Table of Contents:

    Preface: Of Nature and Technology


  1. Welcome to the nanoworld!

  2. II. The role model: The living cell as a nanotechnological factory

  3. Proteins: The cell's nanomachines

    • Molecular motors: muscle research moves on

    • Ways & Means: Structure determination by X-ray crystallography

    • The enzyme that feeds the world

    • Protein movies: Snapshots of an enzyme reaction

    • Profile: Irving Geis -- the art of protein architecture

    • G-proteins: the cell's switchboard

    • Crystals made to measure: Proteins directing crystal growth

  4. From genes to proteins

    • Five minutes for a vital mission: The short life of an insulin molecule

    • Profile: Dorothy Crowfoot-Hodgkin

    • The language of the genes: Linguistic methods help to make sense of DNA

    • Ways & Means: DNA sequencing

    • Death of a dogma: The genetic code is not universal

    • Round and round the ribosome

    • Skiing the energy landscape: The new view of protein folding

    • Ways & Means: Nuclear magnetic resonance spectroscopy

    • Safeguarding adolescent proteins: Molecular chaperones prevent dangerous liaisons

    • Recycling scheme in the cell: Understanding how the proteasome works

  5. Amazing cells

    • Three kinds of cells

    • A different kind of bug: Methanococcus jannaschii

    • Knowing where you're going: Magnetotactic bacteria can tell north from south

    • Cells with a vision: The rods and cones of the retina

    • Cell wars (1): How taxol keeps cancer cells from multiplying

    • Cell wars (2): How bacteria get the better of antibiotics

  6. III. Towards the nanoworld: Biotechnology, supramolecular chemistry, and colloid chemistry pave the way for nanotechnology

  7. From molecules to supramolecules

    • The world's smallest tree: Dendrimers are not just pretty molecules/LI>

    • Writing the amino acid code: The surprising success of protein design

    • A tunnel through the cell membrane: Self-assembling nanotubes

    • Tying the knot: Topological chemistry

    • A few useful things to do with DNA

    • Be fruitful and multiply: Self-replicating peptides

    • Towards artificial enzymes: Synthetic supramolecules compete with catalytic antibodies

  8. From Quantum Dots to Micromachines

    • Divide and discolour: Q-particles are different

    • Gold clusters shine brightly

    • Carbon nanotubes as electronic devices

    • Ways & Means: How to make molecular footballs

    • Carbon nanotubes as AFM tips

    • Ways & Means: Scanning probe microscopies (AFM / STM)

    • Wafer-thin patchwork: The rubber-stamp trick combines nano- and biotechnology

    • "Organic metals" as novel protective coatings

    • Small Wonders: The Era of the Micromachines Has Begun

    • Ways and Means: Photolithography

  9. Biotechnology

    • How to tell right from wrong in genetic engineering

    • The quest for the blue rose: Trying to make a fashion of "blue genes"

    • The green spark: A fluorescent protein helps tracing gene expression

    • Squeezed eggs for breakfast: Why Pressure Cooks Better Than Heat

    • Sleeping Beauty in the glass state: How to preserve biochemicals

  10. IV. A big future for tiny machines?

  11. Which ingredients are needed for a technological revolution?

    • How to start a technological revolution

    • Materials

    • Production methods

    • Miniaturization

    • A definition of the buzz-word "nanotechnology"

  12. Visions of the future

    • The prophets of nanotechnology

    • Propfile: Richard P. Feynman: "There's plenty of room at the bottom"

    • Drexler's brave new world -- a guided tour

    • Profile: K. Eric Drexler

    • Maxwell's demon -- a predecessor of nanotechnology?

    • The future of computation

  13. Nanotechnology today -- nanotechnology tomorrow

    • The "top-down" approach: From micro to nano

    • The "bottom-up" approach: Self organization comes together

    • From old materials to advanced materials

    • A farewell to factories?

    • Nanotechnology -- the next industrial revolution?

  14. V. Appendix

  15. Glossary

  16. Further Reading and Internet Links

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